ISSN 1662-4009 (online)

ey0016.15-1 | (1) | ESPEYB16

15.1. A Copeptin-based approach in the diagnosis of diabetes insipidus

W Fenske , J Refardt , I Chifu , I Schnyder , B Winzeler , J Drummond , A Jr. Ribeiro-Oliveira , T Drescher , S Bilz , DR Vogt , U Malzahn , M Kroiss , E Christ , C Henzen , S Fischli , A Tonjes , B Mueller , J Schopohl , J Flitsch , G Brabant , M Fassnacht , M Christ-Crain

To read the full abstract: N Engl J Med 2018;379:428–439In this multi-centre cohort of 156 patients with hypotonic polyuria, direct measurement of hypertonic saline-stimulated plasma copeptin had much greater diagnostic accuracy than a standard water-deprivation test, as judged by the final reference diagnosis, which was determined on the basis of medical history, test result...